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What Are Gel Shots For Your Knees

How Do I Prepare For Viscosupplementation Treatment For Arthritis

Do Gel Injections For Knee Arthritis Work?

Talk to your healthcare provider about all your medical conditions. Tell your healthcare provider about all the medicines you take, including over-the-counter medicines, like aspirin. Take all of your medicines as normal, unless your healthcare provider tells you otherwise.

The day of your procedure, you can eat and drink as you normally would. Tell your healthcare provider about any new symptoms, like fever. You may want to wear loose clothing so that you can easily expose your joint. Your healthcare provider might give you other instructions about what to do before your procedure.

Caring Medical Research Prolotherapy For Knee Pain

In published research in the Journal of Prolotherapy, Ross Hauser MD investigated the outcomes of patients receiving Prolotherapy treatment for unresolved, difficult to treat knee pain at a charity clinic in Illinois.

  • 80 patients, representing a total of 119 knees, were treated quarterly with Prolotherapy.
  • The results of this study showed that patients had a statistically significant decline in their level of pain, stiffness, crunching sensation, and improvement in their range of motion with Prolotherapy.
  • More than 82% showed improvements in walking ability, medication usage, athletic ability, anxiety, depression, and overall disability with Prolotherapy. Ninety-six percent of patients felt Prolotherapy improved their life overall.

Therapeutic Injections For Osteoarthritis Of The Knee

If physical therapy and pain medication taken by mouth dont relieve the aching pain caused by osteoarthritis of the knee, doctors may recommend an injection of medicine directly into the arthritic joint. Therapeutic injections may give you the relief you need to begin physical therapy or other exercise to strengthen the muscles supporting the knee.

An injection of corticosteroids or hyaluronic acid may reduce inflammation and ease pain. Other more experimental injectionssuch as platelet-rich plasma or stem cellsmay relieve pain and encourage healing in damaged soft tissues. Your doctor can discuss whether you are a candidate for these experimental injections, which are not approved by the U.S. Food and Drug Administration to treat knee osteoarthritis. Some people find that therapeutic injections provide long-term pain relief and help them remain active, but they may not be appropriate for everyone.

Our doctors can use live X-ray or ultrasound imaging to guide the injection precisely into the knee joint, ensuring that the medication has the maximum effect.

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How Are They Taken

You will be given a hyaluronan injection into your joint. This is known as an intra-articular injection.

A nurse or trained healthcare professional will check you carefully and talk about whether the injection is suitable for you. They will give you the injection.

You may receive between one and five injections, usually a week apart, depending on which brand of hyaluronic acid your healthcare professional uses.

For at least two days after the injection, you should avoid jogging, high-impact sports or being overly active. You should also avoid carrying heavy items or standing for long periods.

You might not notice the effect of the injections straight away. Once they start working, any benefits will probably last a few months.

Another Use In Plantaris

Gel Injections for Joint Knee Pain

Some cases of Achilles tendinopathy have a plantaris tendon interfering with the inside of the Achilles tendon. We think that some people have a specific type of anatomy that encourages friction between the two tendons. Recent anecdotal evidence suggests that hyaluronic acid injected between the two tendons reduces this friction and improves pain.

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Caring Medical Research Case Studies

Our research team has published research on patient outcomes and case studies using bone marrow aspirate. Here is a sample of those outcomes. Again, we must remind you that this treatment does not work for everyone. Unfortunately, if you are reading this article you are probably very attuned to medical treatments that do not work.

In the medical journal Clinical Medicine Insights Arthritis and Musculoskeletal Disorders, our Caring Medical research team published our findings in seven patients. The patients who were treated for knee pain are featured below:

Patient case Knee pain: A 69-year-old man

A 69-year-old male came into our office with pain in both knees, with his right knee significantly more painful. Pain resulted in frequent sleep interruption and limitation of exercise.

The patient had received prolotherapy at another office in the previous two years but felt that the treatment has reached its maximum ability to heal.

The patient was diagnosed with osteoarthritis and received five bone marrow/dextrose treatments in each knee at two-month intervals.

  • Two months after the final treatment, the patient reported that he was completely free of pain or stiffness in both knees, had regained full range of motion, no longer suffered sleep interruption, and was no longer limited in exercise or daily life activities.

Patient case Knee pain A 56-year-old woman

The patient received bone marrow/dextrose treatments for six visits with 810 week intervals.

Are Hyaluronic Injections Low

A research letter in the Journal of the American Medical Association Internal Medicine, with the title: Are Hyaluronic injections low-value health care? Using Medicare Data to Understand Low-Value Health Care: The Case of Intra-articular Hyaluronic Acid Injections, backed that up withbased on high-quality evidence that hyaluronic acid injections were not associated with clinically meaningful improvement in symptoms compared with placebo injections.

This statement paper is from 2014, lets see if we can advance the research forward towards 2021.

The first stop is February 2016 and the journal Clinical Orthopaedics and Related Research. It is an editorial from Seth S. Leopold, MD. Here are the quoted learning points:

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Cortisone Shots In Knee: What You Need To Know First

If there ever were a magic bullet for recovering from an injury cortisone shots might be it.

Of course like all magic, it requires distraction from whats truly occurring for it to work. In other words, you might feel like a million bucks, but you havent resolved the cause of the pain and that means it might very well return.

During my first visit with the Orthopedic surgeon he offered me a cortisone shot, while we waited things out with PT to see if surgery was really necessary. I declined having heard various things about long term issues and knowing that overall I wasnt in unbearable pain. Not like in 2007, when I cried in joy when the sports medicine doctor injected my IT Band.

Without my even knowing it, Id made a great choice.

Theres a vast difference between injecting tendons and a cortisone joint injectionso heres what we all need to know before thinking weve found the magic bullet. Cortisone injection side effects in the knee could be substantial.

Are Gel Knee Injections Worth A Shot

Gel Injections For Knee Arthritis Pain PROOF NYC Pain MD

Injections of gel-like substances may be making inroads into the established arsenal of treatments for painful, arthritic knees.

Physical therapy, nutritional supplements, anti-inflammatory painkillers, corticosteroid injections and more help some but not all of the estimated 27 million Americans with osteoarthritis, many trying to stave off joint-replacement surgery. The condition — caused by the breakdown of cartilage in the knee, usually from the wear-and-tear of normal activity over time — leaves too little cushioning between bones in the knee. Pain results, and movement becomes restricted.

So are gel injections, called viscosupplementation, worth a shot?

“My personal experience is with the right patient it does work, and it’s a reasonable choice that’s not terribly invasive,” said Dr. Michael J. Sileo, an orthopedic surgeon specializing in sports medicine in East Setauket. Sileo said he now does at least 300 to 500 gel injections in knees a year, adding that doctors who specialize only in knee treatments probably do many more.


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Dr. James Penna, an assistant professor in the orthopedics department at the Stony Brook University School of Medicine, said he’s also seen benefits from the injections.


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How Do You Prepare For A Gel Shot

It is best to prepare for the treatment by discussing your symptoms and severity of your joint pain with your doctor. There should be clear communication speaking about the procedure and what to expect. Prior to the appointment day, you will have discussed with your physician any specifics you have about the injections.

Gel shots are usually recommended for patients when less invasive treatment options have not provided relief. Gel shot injections can be administered within a standard doctors office visit.

Study: A Comparison Between Prolotherapy Botox Physical Therapy And Hyaluronic Acid Injections

Here we have a September 2020 study published in the International Journal of Rehabilitation Research. In it, researchers compared the effectiveness of four treatments in the management of knee osteoarthritis.

  • In total, 120 patients with knee osteoarthritis, all over the age of 50 years of age were randomly allocated to four groups.
  • The test results were based on pain and functional scoring systems.
  • Exercise recommendations were prescribed daily for all participants throughout the study.
  • For physical therapy , participants received superficial heat, transcutaneous electrical nerve stimulation, and pulsed ultrasound.
  • Botox: Researchers administered a single intra-articular injection of botulinum neurotoxin type A
  • Hyaluronic acid: Researchers administered three injections of hyaluronic acid
  • Prolotherapy: Researchers administered 20% dextrose to patients in the corresponding groups.


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A Brief Understanding Of The Differences Between Prp And Prgf

Studies have shown favor towards the use of plasma rich in growth factors in surgical healing. The difference in the injections is that in plasma rich in growth factors red and white blood cells are removed leaving only the growth factors. The benefit of this is that in wound healing, removing the red and white blood cells will help reduce inflammation. This is why this treatment is more favored in surgical repair. As regenerative medicine outside of surgery relies on controlled inflammation, PRP is seen as a better choice in many situations where there is knee pain.

Here are the highlights of this study:

  • All injection treatments except corticosteroids were found to result in a statistically significant improvement in outcomes when compared with placebo.
  • PRP demonstrated a clinically meaningful difference in function-related improvement when compared with corticosteroids and placebo due to large effect sizes.
  • Studies evaluating outcomes of plasma rich in growth factors reported significant improvement when compared with placebo due to large effect sizes, whereas a potential clinically significant difference was detected in the same comparison parameters in pain evaluation.

Other Injections: Hyaluronic Acid Botox And More

Gel Injections for Joint Knee Pain

Some people have used other types of injections for OA of the knee.

However, experts from the American College of Rheumatology and the Arthritis Foundation dont currently recommend using these, as theres not enough evidence that they work.

Examples of other types of injections include:

  • hyaluronic acid injections, also known as viscosupplementation

You may not know exactly what type of injection youre receiving or what the effect might be.

Always discuss the pros and cons of any treatment with your doctor before starting, so that you can make an informed decision.

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What Are The Potential Risks For A Viscosupplementation Procedure

The most common side effect includes pain at the injection site, swelling, heat, redness, bruising. This can be treated with ice. Inflammation may occur after gel injection, though the symptoms are typically mild and temporary. For this reason, restricted activity is recommended for 48 hours after the treatment.

The most severe risks are infection and bleeding. The treatment is contraindicated in patients with hypersensitivity to sodium hyaluronate preparations and patients with known infections or skin diseases in and around the injection site.

Why Would An Arthritis Patient Get Hyaluronic Acid Injections Vs Other Treatments

Typically, you would try other conservative treatments first, like weight loss, exercise, NSAID medications, and steroid injections. If those dont help, hyaluronic injections may be an option.

Some patients might have other conditions for which for first-line treatments would be contraindicated. Some doctors might use hyaluronic acid injections along with steroid injections as well. I had the injection every week for three weeks along with cortisone injections, Sharon Ruoto told us on Facebook. I did this every six months for years.

Although hyaluronic acid is also available as a pill, the shots are usually preferred. Advantages are targeted relief to the joint with no systemic side effects from pills, and the convenience of not taking pills by mouth, Dr. Miller says. Brand names of the hyaluronic acid shot include Euflexxa, Supartz, and Synvisc-One.

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Will It Fix Everything

Unfortunately, no. Hyaluronic acid injections wont cure all painful knee conditions. However, the injections can be extremely effective for osteoarthritis. Hyaluronic acid injections replenish the lining of your knees, which can provide pain relief for up to six months.

However, the treatment isnt as effective with other painful knee conditions, like ligament tears, tendinitis, or sprains. Hyaluronic acid injections restore the lining of your joints they dont repair your tissue.

Bone Marrow Aspirate Concentrate Or Bone Marrow Concentrate Type Stem Cell Therapy

Do gel injections eliminate knee pain?

Using stem cells taken from a patients bone marrow is becoming a therapy of interest due to the potential of these mesenchymal stem cells to differentiate into other types of cells such as bone and cartilage. This is not a new revolutionary treatment, this treatment has been studied and applied for many years. It is a difficult treatment for some doctors to give. You do need experience in all aspects of the treatment to give the patient the best chance at achieving their healing goals.

Bone Marrow is the liquid spongy-type tissue found in the hallow of bones. It is primarily a fatty tissue that houses stem cells that are responsible for the formation of other cells. These mesenchymal stem cells , also called marrow stromal cells, can differentiate into a variety of cell types including osteoblasts , chondrocytes , myocytes , adipocytes , fibroblasts and others when reintroduced into the body by injection. Bone marrow also contains hematopoietic stem cells that give rise to the white and red blood cells and platelets.

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Injections To Relieve Knee Pain

Knee osteoarthritis is the most common form of osteoarthritis in the United States. It is caused by progressive degeneration of the cartilage in the knee joint, which protects bones in this area from rubbing against each other. While there is no cure for osteoarthritis, also referred to as wear-and-tear arthritis or degenerative joint disease, treatments can help reduce pain and inflammation.

If oral medications do not help with your knee osteoarthritis pain, your healthcare provider may suggest injecting a medication directly into the knee joint. Knee injections used for arthritic pain include corticosteroid , hyaluronic acid , platelet-rich plasma, placental tissue matrix, Botox, and reverse injection .

Comparison Research: Hyaluronic Acid And Prolotherapy Injections

In November 2021 doctors publishing in the American Journal of Physical Medicine & Rehabilitation evaluated the effectiveness of Prolotherapy for pain reduction and improvement of function in individuals with knee osteoarthritis in comparison with hyaluronic acid by meta-analysis . Six studies were included .


In favor of prolotherapy

  • No statistically significant differences were found between prolotherapy and hyaluronic acid in pain control in the short term, however, the sub-analysis were included only the studies that used intra-articular injection within the prolotherapy scheme, an effect was found in favor of the prolotherapy groups.
  • An effect was found in favor of the prolotherapy group in the improvement in function.
  • No major adverse reactions or side effects were reported in any of the studies.
  • Prolotherapy appears to be an effective intervention to decrease pain and improve function in knee osteoarthritis, with efficacy similar to intra-articular injections with hyaluronic acid in the short-term follow-up.

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When Other Treatments Arent Working See If These Shots To Relieve The Painful Symptoms Of Knee Osteoarthritis May Be Right For You

Youve tried all the conservative therapies for your knee osteoarthritis, and nothing is working. You really, really dont want to go down the knee replacement surgery road yet. Whats left to try? You might want to consider hyaluronic acid injections for your knee osteoarthritis . Be warned, though: Their effectiveness is up for debate, with medical research not quite backing up how well they work.

Yet, individual patients have reported relief from their arthritis pain with the shots but not everyone. Even a CreakyJoints Facebook post soliciting feedback on patients experiences received responses ranging from they worked like a dream and amazing to they did nothing to relieve my OA knee pain and even they made my knee worse.

Read on to find out more and decide if hyaluronic acid injections are worth a shot for you.

Research Comparing Prp Injections Cortisone Injections And Hyaluronic Acid Injections

Arthritis Medical Use Hyaluronic Acid Gel Knee Joint Injection

Doctors wrote in a January 2019 study that while PRP injections, cortisone injections, and hyaluronic acid injections are considered equally effective at relieving patient symptoms at three months, at 6, 9, and 12 months the PRP injections delivered significantly better results.

A July 2020 study published in the Journal of Pain Research also suggested that PRP injections provided better results for patients than hyaluronic acid injections. The studys conclusions were: Besides significantly higher satisfaction belonging to the group, there was a statistically significant improvement in pain and function scores at 12 months compared to hyaluronic acid injections

In research published in the Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, PRP was shown to provide significant healing of the meniscus as well as out out-perform hyaluronic acid in patients with knee joint cartilage degeneration. Similar results were documented in the journal Archives of physical medicine and rehabilitation.

An August 2021 paper in the Orthopaedic Journal of Sports Medicine suggests however that corticosteroid and hyaluronic acid injections are favored for different knee problems, while PRP currently has insufficient evidence to make a conclusive recommendation for or against its use.

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