Mayo Clinic Q And A: New Technique For Repairing Knee Cartilage Damage
DEAR MAYO CLINIC: I’m interested in the new procedure approved by the U.S. Food and Drug Administration that can repair cartilage in the knee. How does it work? Who’s a good candidate for this procedure?
ANSWER: The new technique is called matrix-associated autologous chondrocyte implantation, or MACI. It can be effective for repairing isolated cartilage damage in the knee, but it’s not useful for people whose knee cartilage is diffusely damaged due to arthritis.
Your knee has two kinds of cartilage: the articular cartilage and the meniscus. Matrix-associated autologous chondrocyte implantation is used to repair articular cartilage damage, which can come from an isolated injury or defect, or as a result of arthritis.
Of these two problems, isolated injuries and defects are much less common than arthritis. They usually happen due to an athletic injury or another medical condition, such as osteochondritis dissecans. Both isolated cartilage defects and arthritis have similar symptoms, including knee pain, swelling and loss of motion.
With matrix-associated autologous chondrocyte implantation, the new cells are grown on a membrane scaffold in the lab. That’s different than the cartilage repair techniques previously used. In the older approaches, cartilage cells were grown in a lab and implanted into the knee under a patch created from a membrane taken off the outer surface of a bone, called the periosteum, or implanted under a membrane made of collagen.
Initial Treatment And Self Care
If youve injured your joint and your symptoms are not too severe for example, youre still able to put weight on and move the joint you can often look after yourself using PRICE therapy.
PRICE stands for:
- Protection protect the affected area from further injury by using a support, such as a knee brace
- Rest rest the affected joint as much as possible during the first 2 or 3 days , then try gradually returning to light activity over the next few days and weeks
- Ice apply an ice pack or a bag of frozen vegetables wrapped in a towel to the injured area for 15-20 minutes every 2-3 hours during the first 2 or 3 days
- Compression compress or bandage the injured area to limit any swelling and movement that could damage it further you can use a simple elastic bandage or an elasticated tubular bandage available from a pharmacy
- Elevation keep the injured area raised and supported on a pillow whenever you can to help reduce swelling
Visit your GP if your symptoms have not started to improve after a few days of PRICE therapy.
Foods That Increase Bone Cartilage & Regenerate I
Injured cartilage typically does not heal on its own, so doctors have developed several surgical techniques that attempt to repair, regenerate, and replace cartilage. These surgeries can be performed on almost any joint, but they are most commonly performed on knees Researchers at the Stanford University School of Medicine have discovered a way to regenerate, in mice and human tissue, the cushion of cartilage found in joints
Medical Treatments for Cartilage Regrowth. Here are some ways to regenerate/ repair/ replace worn or damaged cartilages: Minimally invasive surgical methods for cartilage repair include options like: Chondroplasty and Debridement. Other methods include: Knee Microfracture, Knee Drilling and Knee Abrasion Arthroplasty The scientists observed that cartilage age was greatest at the hip, moderate at the knee and the youngest cartilage was found in the ankle. This may explain why injuries to ankles heal quicker than those of knees or hip joint injuries, and why there is a lower incidence of ankle arthritis as compared to knee or hip arthritis Humans may lack the salamander skill of regrowing a limb, but a new study suggests they do have some capacity to restore cartilage in their joints. The findings run counter to a widely held belief: Because the cartilage cushioning your joints lack..
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Foods That Help Your Joints
Eating foods good for joints and cartilage may help relieve the symptoms of arthritis and other inflammatory conditions, including osteoarthritis and gout. In some cases, you might even be able to prevent or delay their progression.
Miriam E. Nelson, Ph.D., of Tufts University, states that eating to protect your joints can potentially reduce painful inflammation and annoying stiffness. By adding exercise to a healthy diet, you’ll likely lose weight, which also helps ease the stress on your hip and knee joints. Even a small reduction in body weight is a step in the right direction.
Per Dr. Nelson, you should consume one or more servings of fish, nuts, soy and legumes each day. Limit meat, eggs and poultry to two servings daily. Add three servings of vegetables, three servings of fruits and four to nine servings of starches, with at least half from whole grain sources.
Between two and three servings of reduced-fat milk, cheese and yogurt cover the dairy category. Omega-3 oils are very desirable, but you should limit all other oils and fats. It’s also advisable to limit your consumption of sugary foods.
Dr. Nelson’s recommendations are based on smaller size “servings” rather than heaping portions that often fill diners’ plates. Also, making these healthy foods a priority means your plate won’t have much room for calorie-packed processed foods that don’t provide much nutrition. These principles also provide a good foundation for an osteoarthritis diet.
Cartilage Repair And Transplantation
Articular Cartilage is the white tissue lining the end of bones where these bones connect to form joints. Cartilage acts as cushioning material and helps in smooth gliding of bones during movement. An injury to the joint may damage this cartilage which cannot repair on its own. Cartilage can be damaged with increasing age, normal wear and tear, or trauma. Damaged cartilage cannot cushion the joints during movement and the joints may rub over each other causing severe pain and inflammation.
Cartilage restoration is a surgical procedure where orthopaedic surgeons stimulate the growth of new cartilage that restores the normal function. Arthritis condition can be delayed or prevented through this procedure.
Several techniques are employed for cartilage restoration including dietary supplements, microfracture, drilling, abrasion arthroplasty, osteochondral autograft, and allograft transplantation.
Microfracture: In this method numerous holes are created in the injured joint surface using a sharp tool. This procedure stimulates healing response by creating new blood supply. Blood supply results in growth of new cartilage.
Drilling: In this method a drilling instrument is used to create holes in the injured joint surface. Drilling holes creates blood supply and stimulate growth of new cartilage. Although the method is similar to microfracture, it is less precise and the heat produced during drilling may damage other tissues.
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Meet Dr Britton Who Is Revolutionizing Healthcare And Pain Management
Dr. RKione Britton
Dr. Britton is currently a Board-Eligible Functional Neurologist. Studying functional neuro-kinesiologist through the Carrick Institute. He has already completed over 2000 post-doctoral hours in neuroscience and Kinesiology.
In addition to his Doctor of Chiropractic, Dr. Britton has undertaken additional postgraduate studies. Comprehensive coursework in Functional Neuro-Orthopedic Rehabilitation. He has over 100 hours of training in Professional Kinesiology and is certified in the advanced Myofascial Release soft-tissue technique of NMR. He also practices the Chiropractic BioPhysics® technique for addressing the unique cellular properties of bone that allow for utilizing the bioelectric properties of the skeleton and allow the reversal of degenerative damages to the spine and skeleton.
West LA Neuro-Kinesiology: Nerve, Disc, & Neuropathy
Two terms as President of the Student American Chiropractic Association .
Orange County physician coordinator for Arthritis Introspective, a support group for those with arthritis, inflammatory diseases and autoimmune disorders.
Direct Trauma To Joints
Some people start having cartilage complications when theyre involved in some sort of activity that exposed their joints to heavy impact.
Classic examples are automobile accidents and/or a bad fall such as in contact sports.
Unlike joint disease where the cartilage is literally eaten away, trauma can causetearing of the cartilage or just a displacement of articular cartilage from its usual location.
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Benefits Of Knee Cartilage Replacement
Knee cartilage can cause daily pain and reduced mobility when it has been severely injured or worn down to the point where it no longer provides smooth bone movement within the joint or cushioning between the bones. It is not a condition that will improve on its own.
Repairing or replacing damaged knee cartilage can:
- provide pain relief
Arthroscopic Lavage / Debridement
Arthroscopic lavage is a “cleaning up” procedure of the knee joint. This short-term solution is not considered an articular cartilage repair procedure but rather a palliative treatment to reduce pain, mechanical restriction and inflammation. Lavage focuses on removing degenerative articular cartilage flaps and fibrous tissue. The main target group are patients with very small defects of the articular cartilage.
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Natural Remedy For Cartilage Regeneration Gelatin
It is a supplement to many salads and desserts, and besides being easy to prepare, the gelatin has one advantage it is an excellent natural remedy for knee joint regeneration and other joints as well. Namely, several studies have shown that the consumption of this supplement can significantly help in regeneration of the cartilage.
The optimum quantity is 10 grams per day, and by regular intake it can prevent the uncomfortable symptoms of osteoarthritis. It is rich in protein, it has 10 essential amino acids, including proline and hydroxyproline, that help in regeneration of the muscle tissue.
Another advantage is that the gelatin does not contain fats and cholesterol, which is not the case in most foods that are rich in protein. Besides, it is abound with collagen a substance that is important in building tissues, bones, tendons, ligaments and cartilages, which seem to diminish as the organism gets older.
Can Knee Cartilage Repair Itself
Our bodies have an amazing ability to heal, but that process relies a lot on circulation. When tissue is damaged, our blood brings in oxygen and nutrients to help the tissue repair itself. Blood also carries away debris and toxins formed by the inflammation that goes along with healing. Since it doesnt have blood vessels, can cartilage heal on its own? Unfortunately, any healing that does occur is very limited. In addition to the limited blood flow, cartilage cells dont replace themselves very rapidly. That means it can take a very long time for damaged cells to be replaced with new, healthy cells.
Worse, once cartilage starts to break down, the increase in friction inside the joint can cause additional cartilage damage. Thats why arthritis is called a degenerative disease without treatment, it tends to get worse over time.
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What Causes Cartilage Loss In Your Joint
To fully understand why cartilage loss can be such an issue, you first have to understand why its important. Cartilage is the tissue that covers the ends of your bones where they meet together in your joint. It allows the bones to glide over each other smoothly and fluidly.
If your cartilage has worn away, your bones wont be able to move as smoothly and in severe cases can cause bone on bone friction and intense pain. This may also cause you to have swelling, stiffness, or grinding in your joint. There are three main reasons that you may experience loss of cartilage, including:
Stem Cells And Tissue Engineering
Current research focuses on new ways to make the body grow healthy cartilage tissue. This is called tissue engineering. Growth factors that stimulate new tissue may be isolated and used to induce new cartilage formation.
The use of mesenchymal stem cells is also being investigated. Mesenchymal stem cells are basic human cells obtained from living human tissue, such as bone marrow. When stem cells are placed in a specific environment, they can give rise to cells that are similar to the host tissue.
The hope is that stem cells placed near a damaged joint surface will stimulate hyaline cartilage growth.
Tissue engineering procedures are still at an experimental stage. Most tissue engineering is performed at research centers as part of clinical trials.
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Fiber: The Solution On Your Plate
High Fiber Foods and Their Benefits by Urbanwired1 Flickr
The key to alleviating and even avoiding knee pain might be closer than you think! Just look down at your plate. Are you eating enough fiber?
New research in the journal Annals of the Rheumatic Diseases has shown that people with fiber-rich diets have a reduced risk of knee osteoarthritis. This is huge, as two separate studies consistently showed that higher total fiber intake was related to lower risk, with statistically significant results!
The first study, Osteoarthritis Initiative, examined nearly 5,000 participants and the second study, the Framingham Offspring, examined more than 1,200. Both studies concluded that the more fiber you eat, the less likely you are to experience knee pain, and the less likely you are to be diagnosed with knee arthritis.
Keep in mind that correlation does not imply causation, and the studies did not prove that fiber heals knee pain, only that something is going on with the nutrients that are almost certainly good for you.
A Natural Remedy To Regenerate Hip And Knee Cartilage
Some people suffer from osteoarthritis or arthritis. This problem occurs when the cartilage wears out. The cartilages act as buffers between the bones and allow them to articulate smoothly against each other.
When this wear is generated, the bones no longer have how to separate and begin to rub against each other. Because of this, people may experience symptoms such as pain, inflammation and the inability to move.
After a while, the joints begin to deform and change their appearance. Moreover, there are some cases when spurs develop around them. The pieces of bone that can be detached are usually embedded in that free space that leaves the worn joint causing more pain.
People who suffer from this chronic disease are limited by the lack of progressive movement that occurs in legs, arms, and hands. In most cases, this disease affects older people, mostly women.
If you suffer from osteoarthritis or arthritis, we would like to present you with a natural remedy to regenerate hip and knee cartilage. This natural remedy works wonders, because it can help you reduce inflammation and pain. Scroll down to see the recipe for this natural remedy!
You need ingredients such as:
-1 tbsp of thyme
-1 spoonful of mint or spearmint
-1 spoonful of sage
-1 liter of water
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How To Build Cartilage In Knee Naturally & Powerrebound
How To Quickly Regenerate Damaged Cartilage
14 March, 2019
One of the most common injuries for people is damaged cartilage. It tends to be very painful but recent studies have conducted that your diet helps you regenerate cartilage even faster.
Cartilage is a very flexible structure that weightlessly supports certain structures like the pinna , nose, and joints. There are areas in our body that are much more sensitive to getting injured, such as the knee joints, and are always more affected in those who do daily physical activities like athletes.
It can also affect elderly people because of the natural deterioration of the body at a certain age.
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How To Regrow Collagen In The Knee
Collagen is a plentiful protein and vital component of muscles, organs, skin, tendons and connective tissue, such as cartilage. Cartilage, found in the knee and throughout the body, acts as shock-absorbing padding between bones, protecting joints and facilitating movement. With age, collagen production slows and cartilage degenerates, often resulting in pain, stiffness and inflammation that can lead to osteoarthritis. Food alone canât replace collagen in your knee joints, but certain nutrients can help preserve the collagen you have and optimize your bodys own collagen synthesis.
Is This The Gateway To Limb Regeneration Research
These two findings lay important groundwork for future research because, one day soon, scientists will be able to identify those cells in salamanders not found in humans which enable salamanders to regenerate entire limbs.
When this happens, perhaps researchers will be able to reproduce these regenerator cells and create a cocktail mixture with human MicroRNA that can be injected into humans to repair joint injuries or maybe be developed into medicines that can prevent or reverse arthritis.
And, who knows? Maybe one day in the not too distant future, scientists will discover the key to regenerating entire human limbs so we humans can channel our inner salamander!
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